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tongchangzairetuihouchuxianpizhenhehuonianmozhendengbingbian，danyouxiebinglibingbiankenengchuxianzaiqianquqihuoquanshenzhengzhuangzhiqian。pizhenkedangehuoduoge，tongchangpizhenjingguobanzhen、qiuzhen、paozhen、nongpaohejiejiajieduan，butongjieduanpizhenketongshicunzai。kebanmingxianyangganhetengtong。houdoubingbiankeleijikouqiangyanhounianmo、gangmen、zhichang、shengzhiqi、jiemohejiaomodeng。jiejiatuoluohoukeyiliuhongbanhuosesuchenzhe，shenzhibanhen，banhenchixushijiankechangdashunian。houdoubingchengyue2-4zhou。daduoshubingliweizixianxingjibing，zhengzhuanghuizixingxiaoshi，yeyouzhongzhenghesiwangfasheng，zhuyaoweiertong、yunfuhemianyidixiarenqun。2022nian，quanqiufeidifangxingliuxingquganranhuanzhedebingsilvyue0.1%。yujiwangyiqing（1970nianzhi2021nian）xiangbi，2022nianyilaiquanqiuduoguohoudoubaofayiqingbinglizhong，daduoshulinchuangbiaoxianjiaoqing，youxiemeiyouqianquzhengzhuang、pizhenshaohuomeiyoupizhen，gengduodichuxianshengzhiqi、gangmenjigangmenzhichangnianmobingbian，kefashengsaixianyan、guitouyan、niaozhuliuhezhichangyandeng，bingfazhengyounaomonaoyan、guangfandehuaisixingbingbian，keleijiduoqiguan，siwangbinglizhanbaogaobingliyue0.1%，zhuyaoweijiwangweidedaozhiliaodeaizibingbingduganranzhedengmianyilidixiarenqun。 通(tong)常(chang)在(zai)热(re)退(tui)后(hou)出(chu)现(xian)皮(pi)疹(zhen)和(he)或(huo)黏(nian)膜(mo)疹(zhen)等(deng)病(bing)变(bian)，(，)但(dan)有(you)些(xie)病(bing)例(li)病(bing)变(bian)可(ke)能(neng)出(chu)现(xian)在(zai)前(qian)驱(qu)期(qi)或(huo)全(quan)身(shen)症(zheng)状(zhuang)之(zhi)前(qian)。(。)皮(pi)疹(zhen)可(ke)单(dan)个(ge)或(huo)多(duo)个(ge)，(，)通(tong)常(chang)皮(pi)疹(zhen)经(jing)过(guo)斑(ban)疹(zhen)、(、)丘(qiu)疹(zhen)、(、)疱(pao)疹(zhen)、(、)脓(nong)疱(pao)和(he)结(jie)痂(jia)阶(jie)段(duan)，(，)不(bu)同(tong)阶(jie)段(duan)皮(pi)疹(zhen)可(ke)同(tong)时(shi)存(cun)在(zai)。(。)可(ke)伴(ban)明(ming)显(xian)痒(yang)感(gan)和(he)疼(teng)痛(tong)。(。)猴(hou)痘(dou)病(bing)变(bian)可(ke)累(lei)及(ji)口(kou)腔(qiang)咽(yan)喉(hou)黏(nian)膜(mo)、(、)肛(gang)门(men)、(、)直(zhi)肠(chang)、(、)生(sheng)殖(zhi)器(qi)、(、)结(jie)膜(mo)和(he)角(jiao)膜(mo)等(deng)。(。)结(jie)痂(jia)脱(tuo)落(luo)后(hou)可(ke)遗(yi)留(liu)红(hong)斑(ban)或(huo)色(se)素(su)沉(chen)着(zhe)，(，)甚(shen)至(zhi)瘢(ban)痕(hen)，(，)瘢(ban)痕(hen)持(chi)续(xu)时(shi)间(jian)可(ke)长(chang)达(da)数(shu)年(nian)。(。)猴(hou)痘(dou)病(bing)程(cheng)约(yue)2(2)-(-)4(4)周(zhou)。(。)大(da)多(duo)数(shu)病(bing)例(li)为(wei)自(zi)限(xian)性(xing)疾(ji)病(bing)，(，)症(zheng)状(zhuang)会(hui)自(zi)行(xing)消(xiao)失(shi)，(，)也(ye)有(you)重(zhong)症(zheng)和(he)死(si)亡(wang)发(fa)生(sheng)，(，)主(zhu)要(yao)为(wei)儿(er)童(tong)、(、)孕(yun)妇(fu)和(he)免(mian)疫(yi)低(di)下(xia)人(ren)群(qun)。(。)2(2)02(2)2(2)年(nian)，(，)全(quan)球(qiu)非(fei)地(di)方(fang)性(xing)流(liu)行(xing)区(qu)感(gan)染(ran)患(huan)者(zhe)的(de)病(bing)死(si)率(lv)约(yue)0.(.)1(1)%(%)。(。)与(yu)既(ji)往(wang)疫(yi)情(qing)（(（)1(1)9(9)7(7)0年(nian)至(zhi)2(2)02(2)1(1)年(nian)）(）)相(xiang)比(bi)，(，)2(2)02(2)2(2)年(nian)以(yi)来(lai)全(quan)球(qiu)多(duo)国(guo)猴(hou)痘(dou)暴(bao)发(fa)疫(yi)情(qing)病(bing)例(li)中(zhong)，(，)大(da)多(duo)数(shu)临(lin)床(chuang)表(biao)现(xian)较(jiao)轻(qing)，(，)有(you)些(xie)没(mei)有(you)前(qian)驱(qu)症(zheng)状(zhuang)、(、)皮(pi)疹(zhen)少(shao)或(huo)没(mei)有(you)皮(pi)疹(zhen)，(，)更(geng)多(duo)地(di)出(chu)现(xian)生(sheng)殖(zhi)器(qi)、(、)肛(gang)门(men)及(ji)肛(gang)门(men)直(zhi)肠(chang)黏(nian)膜(mo)病(bing)变(bian)，(，)可(ke)发(fa)生(sheng)腮(sai)腺(xian)炎(yan)、(、)龟(gui)头(tou)炎(yan)、(、)尿(niao)潴(zhu)留(liu)和(he)直(zhi)肠(chang)炎(yan)等(deng)，(，)并(bing)发(fa)症(zheng)有(you)脑(nao)膜(mo)脑(nao)炎(yan)、(、)广(guang)泛(fan)的(de)坏(huai)死(si)性(xing)病(bing)变(bian)，(，)可(ke)累(lei)及(ji)多(duo)器(qi)官(guan)，(，)死(si)亡(wang)病(bing)例(li)占(zhan)报(bao)告(gao)病(bing)例(li)约(yue)0.(.)1(1)%(%)，(，)主(zhu)要(yao)为(wei)既(ji)往(wang)未(wei)得(de)到(dao)治(zhi)疗(liao)的(de)艾(ai)滋(zi)病(bing)病(bing)毒(du)感(gan)染(ran)者(zhe)等(deng)免(mian)疫(yi)力(li)低(di)下(xia)人(ren)群(qun)。(。)&(&)n(n)b(b)s(s)p(p);(;)